Resistance to antibiotics can be transferred...

Science (April 11, 2011)

Part of the bacterial DNA, which often leads to antibiotic resistance is a master at moving between different types of bacteria and adapting themselves to different types of bacteria, suggests research conducted by the research team from the University of Gothenburg in collaboration with Chalmers University of Technology. The study published in articles in the scientific journal Nature Communications. More and more bacteria are becoming resistant to our common antibiotics, and worse, more and more are becoming resistant to all known antibiotics. This problem is known as multi-resistance, and is usually described as one of the most significant threats in the future, public resistance to antibiotics health may occur in bacteria in the environment and our bodies. Resistance to antibiotics can be transferred to bacteria that cause human disease, even if bacteria are not related to each other. Most of gene transfer between bacteria occurs via the so-called related plasmids, of bacterial DNA. Plasmids can exist and multiply inside cells, where it uses the mechanisms of cell and then be transferred to another cell, and thus distributed among bacteria. The research team studied a group of known carriers of genes for antibiotic resistance: IncP-1 plasmids. Using advanced DNA analysis, researchers have achieved success in mapping the origin of different IncP-1 plasmids and their mobility between different types of bacteria. Our results show that plasmids from the IncP-1 group existed, and adapted to widely different bacteria. They also recombination, which means that a plasmid can be regarded as part of a mosaic of genes, each adapted to different types of bacteria, says Peter Norberh, a researcher at the Institute of Biomedicine at the University of Gothenburg. This indicates very good adaptability and suggests that these plasmids can move relatively freely between them, and thrive in, many different kinds of bacteria. IncP-1 plasmids are very powerful "vehicles for the transport of antibiotic resistance genes from species of bacteria. Therefore, it is not important, the environment in which part of the world, or that species of bacteria resistance to antibiotics occurs. Resistance genes can be relatively easily transported from the original medium for bacteria that infect man by IncP-1 plasmid or other plasmids with similar properties as "vehicles", says Professor Malte Hermansson Department of Cell and Molecular Biology at the University of Gothenburg. It has been known for some time that plasmids play an important role in the spread of resistance to antibiotics. The results of the research team suggests that IncP-1 plasmids can move, and moved between various types of bacteria and also interacted directly with each other, which may increase the potential for spread of genes. Recommend this story on Facebook, Twitter

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and Google +1: Other Bookmark and collaboration: History Source: above story buy strattera online is reprinted with provided through, services AAAS. Note: materials may be edited for content and length. For more information, please contact the source listed above. Journal Links Norberh Peter, Mary Bergstrm, Vinay Jethava, Devdatt Dubhashi, Malte Hermansson. IncP-1 plasmid backbone adapts to different host species of bacteria and developed by homologous recombination. Nature Communications, 2011, 2: 272 DOI:

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